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Tomatoes and lycopene

Tomatoes and lycopene

Tonatoes 1. Tomatoes and lycopene, the evidence thus far is mainly suggestive, and the underlying snd are not clearly understood. Natural antioxidants in human health and disease. Acyclic Phytol Geranylgeranyl pyrophosphate Geranyl-linalool. Published Jan The Best Sweet Wines from Italy The Best Red Wines from Italy — Vintage The Best Red Wines from Germany — Vintage The Best Red Wines from Austria — Vintage The Best Grüner Veltliners from Lower Austria - Vintage

Tomatoes and lycopene -

Lycopene is non-toxic and commonly found in the diet, mainly from tomato products. There are cases of intolerance or allergic reaction to dietary lycopene, which may cause diarrhea , nausea , stomach pain or cramps, gas, and loss of appetite.

Lycopene may affect the immune system , the nervous system , sensitivity to sunlight, or drugs used for stomach ailments. Lycopenemia is an orange discoloration of the skin that is observed with high intakes of lycopene. A review of randomized controlled trials found conflicting evidence for lycopene having an effect on cardiovascular risk factors , [29] whereas a review concluded that tomato products and lycopene supplementation reduced blood lipids and blood pressure.

A review found that dietary lycopene was associated with reduced risk of prostate cancer , [31] whereas a meta-analysis found that dietary lycopene did not affect prostate cancer risk.

In a review of literature on lycopene and its potential benefit in the diet, the European Food Safety Authority concluded there was insufficient evidence for lycopene having antioxidant effects in humans, particularly in skin, heart function, or vision protection from ultraviolet light.

Although lycopene from tomatoes has been tested in humans for cardiovascular diseases and prostate cancer, no effect on any disease was found. no studies provided information about whether lycopene intake may reduce the risk of any of the specific forms of cancer.

Based on the above, FDA concludes that there is no credible evidence supporting a relationship between lycopene consumption, either as a food ingredient, a component of food, or as a dietary supplement, and any of these cancers. Contents move to sidebar hide.

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Download as PDF Printable version. In other projects. Wikimedia Commons. Carotenoid pigment. CAS Number. Interactive image. CHEBI Y. ChEMBL Y. PubChem CID. SB0N2N0WV6 Y. CompTox Dashboard EPA. Chemical formula. Solubility in water.

Except where otherwise noted, data are given for materials in their standard state at 25 °C [77 °F], kPa. Y verify what is Y N? Infobox references. Chemical compound. PubChem, US National Library of Medicine. Retrieved 13 October CRC Handbook of Chemistry and Physics 92nd ed.

CRC Press. ISBN Kirk-Othmer Encyclopedia of Chemical Technology. doi : Conde Nast. Retrieved Micronutrient Information Center, Linus Pauling Institute, Oregon State University, Corvallis, OR.

July Archived from the original on 21 May Retrieved 29 May Tomato lycopene extract" PDF. US Food and Drug Administration. R; Agarwal, Anita; Chakravarthi, Sujatha; Agarwal, Sanjiv; Rao, A. Venket Journal of Molecular Structure: Theochem. The Journal of Nutrition.

PMID Retrieved 10 May Bibcode : PhRvB.. Archived from the original PDF on Eating tomatoes may also help lower your risk of stroke, likely due to the lycopene they contain. Lycopene is a carotenoid—a family of pigments that give fruits and vegetables their brilliant red, orange, and yellow coloring.

Lycopene is also a powerful antioxidant that eliminates dangerous free radicals that can damage DNA and other fragile cell structures. Edward Giovannucci, a professor of nutrition and epidemiology at the Harvard School of Public Health. Past research, some of it done by Dr.

Giovannucci, has shown that a diet rich in lycopene-containing foods may help lower the risk of prostate and other cancers. Now, in a report just published in the journal Neurology , a team of Finnish researchers has linked lycopene levels in the blood to stroke protection. They made this connection after following more than a thousand middle-aged men for 12 years.

The finding came as a surprise—the researchers initially wanted to know if other antioxidants affected strokes, such as alpha carotene, beta carotene, vitamin A, and vitamin E. The researchers suggested that lycopene, in addition to its ability to attack free radicals, may also reduce inflammation and cholesterol, improve immune function, and prevent blood from clotting.

All of these may help reduce ischemic strokes, which are caused by clot-caused blockages in blood flow to the brain. Most of that is plausible, says Dr.

But we still need larger studies to confirm the findings and to figure out if the stroke protection is due to lycopene or healthy lifestyle habits. Still, he says the benefits of lycopene for both cancer and stroke protection are very promising. Personally, this makes me want to increase my tomato intake.

Slice of tomato on my turkey sandwich? So yesterday. Hello, glass of tomato juice at every meal. He recommends at least 10, micrograms of lycopene per day—from food. Tomato-based products do, of course, give you the most bang for your buck. You may be getting the wrong form of lycopene in a supplement.

So stick to a diet that includes some lycopene-rich foods. Tomato lycopene and low density lipoprotein oxidation: a human dietary intervention study. Lipids ; 33 : Bioavailability and in vivo antioxidant properties of lycopene from tomato products and their possible role in the prevention of cancer.

Nutr Cancer ; 31 : Pool-Zobel BL, Bub A, Muller H, Wollowski I, Rechkemmer G. Consumption of vegetables reduces genetic damage in humans: first result of a human intervention trial with carotenoid-rich foods.

Carcinogenesis ; 18 : Effect of diet and smoking on serum lycopene and lipid peroxidation. Nutr Res ; 18 : Rao AV, Fleshner N, Agarwal S. Serum and tissue lycopene and biomarkers of oxidation in prostate cancer patients: a case control study.

Nutr Cancer ; 33 : La Vecchia C. Mediterranean epidemiological evidence on tomatoes and the prevention of digestive tract cancers. Proc Soc Exp Biol Med ; : Giovannucci E. Tomatoes, tomato-based products, lycopene, and cancer: review of the epidemiologic literature.

J Natl Cancer Inst ; 91 : Tomatoes and risk of digestive-tract cancers. Int J Cancer ; 59 : Colditz GA, Branch LG, Lipnick RJ, Willett WC, Rosner B, Posner BM, et al. Increased green and yellow vegetable intake and lowered cancer deaths in an elderly population.

Am J Clin Nutr ; 41 : 32 Giovannucci E, Ascherio A, Rimm EB, Stampfer MJ, Colditz GA, Willett WC. Intake of carotenoids and retinol in relation to risk of prostate cancer. J Natl Cancer Inst ; 87 : Dorgan JF, Sowell A, Swanson CA, Potischman N, Miller R, Schussler N, et al.

Relationship of serum carotenoids, retinol, α-tocopherol, and selenium with breast cancer risk: results from a prospective study in Columbia, Missouri United States. Cancer Causes Control ; 9 : 89 Gann P, Ma J, Giovannucci E, Willett W, Sacks FM, Hennekens CH, et al.

Lower prostate cancer risk in men with elevated plasma lycopene levels: results of a prospective analysis. Cancer Res ; 59 : Kucuk O, Sakr FH, Djuric Z, Li YW, Velazquez F, Banerjee M, et al. Lycopene supplementation in men with prostate cancer PCa reduces grade and of preneoplasia PIN and tumor, decreases serum prostate specific antigen and modulates biomarkers of growth and differentiation [abstract P1.

Parthasarathy S, Steinberg D, Witztum JL. The role of oxidized low-density lipoproteins in pathogenesis of atherosclerosis. Annu Rev Med ; 43 : Heller FR, Descamps O, Hondekijn JC. LDL oxidation: therapeutic perspectives.

Atherosclerosis ; Suppl :S Parthasarathy S. Mechanism by which dietary antioxidants may prevent cardiovascular diseases. J Med Food ; 1 : 45 Morris DL, Kritchevsky SB, Davis CE. Serum carotenoids and coronary heart disease: the Lipid Research Clinics Coronary Primary Prevention Trial and Follow-up Study.

JAMA ; : Hodis HN, Mack WJ, LaBree L, Cashin-Hemphill L, Sevanian A, Johnson R, et al. Serial coronary angiographic evidence that antioxidant vitamin intake reduces progression of coronary artery atherosclerosis. Paolisso G, Gambardella A, Giugliano D, Galzerano D, Amato L, Volpe C, et al.

Chronic intake of pharmacological doses of vitamin E might be useful in the therapy of elderly patients with coronary heart disease. Am J Clin Nutr ; 61 : Heart Outcomes Prevention Evaluation Study Investigators. Vitamin E supplementation and cardiovascular events in high-risk patients.

Kohlmeier L, Kark JD, Gomez-Gracia E, Martin BC, Steck SE, Kardinaal AF, et al. Lycopene and myocardial infarction risk in the EURAMIC Study. Handelman GJ, Parker L, Cross CE. Destruction of tocopherols, carotenoids and retinol in human plasma by cigarette smoke.

Am J Clin Nutr ; 63 : Kristenson M, Zieden B, Kucinskiene Z, Elinder LS, Bergdahl B, Elwing B, et al. Antioxidant state and mortality from coronary heart disease in Lithuanian and Swedish men: concomitant cross sectional study of men aged BMJ ; : Rao AV, Waseem Z, Agarwal S.

Lycopene contents of tomatoes and tomato products and their contribution to dietary lycopene. Food Res Int ; 31 : Uptake of lycopene and its geometrical isomers is greater from heat-processed than from unprocessed tomato juice in humans. Gärtner C, Stahl W, Sies H. Lycopene is more bioavailable from tomato paste than from fresh tomatoes.

Am J Clin Nutr ; 66 : Johnson EJ, Qin J, Krinsky NI, Russell RM. Ingestion by men of a combined dose of β-carotene and lycopene does not affect the absorption of β-carotene but improves that of lycopene. Previous Next. Back to top. In this issue CMAJ Vol. Table of Contents Index by author.

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Citation Tools. Tomato lycopene and its role in human health and chronic diseases. Sanjiv Agarwal , Akkinappally Venketeshwer Rao. CMAJ Sep , 6 ;. Citation Manager Formats BibTeX Bookends EasyBib EndNote tagged EndNote 8 xml Medlars Mendeley Papers RefWorks Tagged Ref Manager RIS Zotero.

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Related Articles No related articles found. PubMed Google Scholar. Dietary antioxidants and year lung function decline in adults from the ECRHS survey. Effects of antiplatelet components of tomato extract on platelet function in vitro and ex vivo: a time-course cannulation study in healthy humans.

Combined Lycopene and Vitamin E Treatment Suppresses the Growth of PCC Human Prostate Cancer Cells in Nude Mice. The Role of Tomato Products and Lycopene in the Prevention of Prostate Cancer: A Meta-Analysis of Observational Studies. Variations in Plasma Lycopene and Specific Isomers over Time in a Cohort of U.

Tomatoes are Hair growth methods of the Tomatoes and lycopene sources of lycopene, the Tomtoes that gives red lgcopene pink fruits their colour Tomatoess Tomatoes and lycopene linked to a range of health benefits. All content. Tomatoex in. Tomatoes Tomatoes and lycopene the biggest food source for lycopene. Victoria Daskal. Lycopene, a type of organic pigment that falls into the category of carotenoids, is related to beta-carotene found in carrots and sweet potatoes which gives certain fruits and vegetables their red-orange hue. Lycopene is a powerful antioxidant that has been linked to health benefits ranging from heart health to protection against sunburn and certain types of cancers. Tomatoes and lycopene


The Benefits of Lycopene

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